Acetaminophen Injection injection is used together with other medicines (eg, narcotic pain relievers) to relieve moderate to severe pain.

Acetaminophen Injection is used to relieve mild to moderate pain and reduce fever in patients. It does not become habit-forming when taken for a long time. Acetaminophen Injection may cause unwanted effects when taken in large doses, including liver damage.

Acetaminophen Injection is available only with your doctor’s prescription.

Acetaminophen Injection indications

Acetaminophen Injection provides temporary relief of minor aches and pains, temporary relief of fever and discomfort due to colds and “flu,” and of simple pain and discomfort due to teething, immunizations and tonsillectomy.

How should I use Acetaminophen Injection?

Use Acetaminophen Injection injection as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Acetaminophen Injection injection is usually given as an injection at your doctor’s office, hospital, or clinic. If you will be using Acetaminophen Injection injection at home, a health care provider will teach you how to use it. Be sure you understand how to use Acetaminophen Injection injection. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Do not mix other medicines (especially chlorpromazine or diazepam) in the same container or IV line as Acetaminophen Injection injection. Contact your health care provider if you have any questions about how to give Acetaminophen Injection injection with other medicines.
• Do not use Acetaminophen Injection injection if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
• Use Acetaminophen Injection injection within 6 hours after opening.
• If you miss a dose of Acetaminophen Injection injection and you are using it regularly, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen Injection injection.

Uses of Acetaminophen Injection in details

This drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.

How to use Acetaminophen Injection (Acetaminophen Injection)

Take this product by mouth as directed. Follow all directions on the product package. If you are uncertain about any of the information, consult your doctor or pharmacist.

There are many brands and forms of Acetaminophen Injection available. Read the dosing instructions carefully for each product because the amount of Acetaminophen Injection may be different between products. Do not take more Acetaminophen Injection than recommended.

If you are giving Acetaminophen Injection to a child, be sure you use a product that is meant for children. Use your child’s weight to find the right dose on the product package. If you don’t know your child’s weight, you can use their age.

For suspensions, shake the medication well before each dose. Some liquids do not need to be shaken before use. Follow all directions on the product package. Measure the liquid medication with the provided dose-measuring spoon/dropper/syringe to make sure you have the correct dose. Do not use a household spoon.

For rapidly-dissolving tablets, chew or allow to dissolve on the tongue, then swallow with or without water. For chewable tablets, chew thoroughly before swallowing.

Do not crush or chew extended-release tablets. Doing so can release all of the drug at once, increasing the risk of side effects. Also, do not split the tablets unless they have a score line and your doctor or pharmacist tells you to do so. Swallow the whole or split tablet without crushing or chewing.

For effervescent tablets, dissolve the dose in the recommended amount of water, then drink.

Pain medications work best if they are used as the first signs of pain occur. If you wait until the symptoms have worsened, the medication may not work as well.

Do not take this medication for fever for more than 3 days unless directed by your doctor. For adults, do not take this product for pain for more than 10 days (5 days in children) unless directed by your doctor. If the child has a sore throat (especially with high fever, headache, or nausea/vomiting), consult the doctor promptly.

Tell your doctor if your condition persists or worsens or if you develop new symptoms. If you think you may have a serious medical problem, get medical help right away.

Acetaminophen Injection description

Acetaminophen Injection (with the Optizorb formulation) also contains the following excipients: Pregelatinized maize starch, calcium carbonate, alginic acid, crospovidone, povidone, magnesium stearate, colloidal anhydrous silica, parahydroxybenzoates (sodium methyl, ethyl and propyl), OPADRY YS-1-7003 white, carnauba wax, purified water.

It contains no sugar, lactose or gluten.

Acetaminophen Injection dosage

Usual Adult Dose for Fever:

IV:

Adults and adolescents weighing 50 kg and over: 1000 mg every 6 hours or 650 mg every 4 hours, with a maximum single dose of 1000 mg, a minimum dosing interval of 4 hours, and a maximum daily dose of Acetaminophen Injection of 4000 mg per day.

Adults and adolescents weighing under 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours, with a maximum single dose of 15 mg/kg, a minimum dosing interval of 4 hours, and a maximum daily dose of Acetaminophen Injection of 75 mg/kg per day.

Orally or Rectally:General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours

No dose adjustment is required when converting between oral and IV Acetaminophen Injection dosing in adults and adolescents. The maximum daily dose of Acetaminophen Injection is based on all routes of administration

(i.e. intravenous, oral, and rectal) and all products containing Acetaminophen Injection.

Usual Adult Dose for Pain:

IV:

Adults and adolescents weighing 50 kg and over: 1000 mg every 6 hours or 650 mg every 4 hours, with a maximum single dose of 1000 mg, a minimum dosing interval of 4 hours, and a maximum daily dose of Acetaminophen Injection of 4000 mg per day.

Adults and adolescents weighing under 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours, with a maximum single dose of 15 mg/kg, a minimum dosing interval of 4 hours, and a maximum daily dose of Acetaminophen Injection of 75 mg/kg per day.

Orally or Rectally:General Dosing Guidelines: 325 to 650 mg every 4 to 6 hours or 1000 mg every 6 to 8 hours

No dose adjustment is required when converting between oral and IV Acetaminophen Injection dosing in adults and adolescents. The maximum daily dose of Acetaminophen Injection is based on all routes of administration

(i.e. intravenous, oral, and rectal) and all products containing Acetaminophen Injection.

Usual Pediatric Dose for Fever:

Preterm neonates 28 to 32 weeks:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 12 hours

Oral: 10 to 12 mg/kg/dose every 6 to 8 hoursMaximum oral daily dose: 40 mg/kg/day

Rectal: 20 mg/kg/dose every 12 hours

Maximum rectal daily dose: 40 mg/kg/day

Preterm neonates 32 to 37 weeks and term neonates less than 10 days:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours

Oral: 10 to 15 mg/kg/dose every 6 hoursMaximum daily dose: 60 mg/kg/day

Rectal: Loading dose: 30 mg/kg; then 15 mg/kg/dose every 8 hours

Maximum daily dose: 60 mg/kg/day

Term neonates greater than or equal to 10 days:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours

Oral: 10 to 15 mg/kg/dose every 4 to 6 hoursMaximum daily dose: 90 mg/kg/day

Rectal: Loading dose: 30 mg/kg; then 20 mg/kg/dose every 6 to 8 hours

Maximum daily dose: 90 mg/kg/day

Infants and Children:

IV: Less than 2 years: 7.5 to 15 mg/kg/dose every 6 hours

Maximum daily dose: 60 mg/kg/day

IV: 2 to 12 years: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours

Maximum single dose 15 mg/kg

Maximum total daily dose: 75 mg/kg/day not to exceed 3750 mg/day

Oral: 10 to 15 mg/kg/dose every 4 to 6 hours as needed; do not exceed 5 doses in 24 hours

Alternatively, the manufacturer lists the following recommended doses:

2.7 to 5.3 kg or 6 to 11 pounds: 0 to 3 months: 40 mg

5.4 to 8.1 kg or 12 to 17 pounds: 4 to 11 months: 80 mg

8.2 to 10.8 kg or 18 to 23 pounds: 1 to 2 years: 120 mg

10.9 to 16.3 kg or 24 to 35 pounds: 2 to 3 years: 160 mg

16.4 to 21.7 kg or 36 to 47 pounds: 4 to 5 years: 240 mg

21.8 to 27.2 kg or 48 to 59 pounds: 6 to 8 years: 320 mg

27.3 to 32.6 kg or 60 to 71 pounds: 9 to 10 years: 400 mg

32.7 to 43.2 kg or 72 to 95 pounds: 11 years: 480 mg

The manufacturer recommends the use of weight to select the dose as the preferred method. If weight is not available, then age may be used.

Rectal: 10 to 20 mg/kg/dose every 4 to 6 hours as needed (Although the perioperative use of high dose rectal Acetaminophen Injection (e.g., 25 to 45 mg/kg/dose) has been investigated in several studies, its routine use remains controversial; optimal doses and dosing frequency to ensure efficacy and safety have not yet been established; further studies are needed).

Children greater than or equal to 12 years:

IV: Less than 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours

Maximum single dose: 750 mg/dose

Maximum total daily dose: 75 mg/kg/day (less than or equal to 3750 mg/day)

IV: Greater than or equal to 50 kg: 650 mg every 4 hours or 1000 mg every 6 hours

Maximum single dose: 1000 mg/dose

Maximum total daily dose: 4000 mg/day

Oral or Rectal: 325 to 650 mg every 4 to 6 hours or 1,000 mg 3 to 4 times daily

Maximum daily dose: 4000 mg/day

Usual Pediatric Dose for Pain:

Preterm neonates 28 to 32 weeks:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 12 hours

Oral: 10 to 12 mg/kg/dose every 6 to 8 hoursMaximum oral daily dose: 40 mg/kg/day

Rectal: 20 mg/kg/dose every 12 hours

Maximum rectal daily dose: 40 mg/kg/day

Preterm neonates 32 to 37 weeks and term neonates less than 10 days:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours

Oral: 10 to 15 mg/kg/dose every 6 hoursMaximum daily dose: 60 mg/kg/day

Rectal: Loading dose: 30 mg/kg; then 15 mg/kg/dose every 8 hours

Maximum daily dose: 60 mg/kg/day

Term neonates greater than or equal to 10 days:

IV loading dose: 20 mg/kg followed by 10 mg/kg/dose every 6 hours

Oral: 10 to 15 mg/kg/dose every 4 to 6 hoursMaximum daily dose: 90 mg/kg/day

Rectal: Loading dose: 30 mg/kg; then 20 mg/kg/dose every 6 to 8 hours

Maximum daily dose: 90 mg/kg/day

Infants and Children:

IV: Less than 2 years: 7.5 to 15 mg/kg/dose every 6 hours

Maximum daily dose: 60 mg/kg/day

IV: 2 to 12 years: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours

Maximum single dose 15 mg/kg

Maximum total daily dose: 75 mg/kg/day not to exceed 3750 mg/day

Oral: 10 to 15 mg/kg/dose every 4 to 6 hours as needed; do not exceed 5 doses in 24 hours

Alternatively, the manufacturer lists the following recommended doses:

2.7 to 5.3 kg or 6 to 11 pounds: 0 to 3 months: 40 mg

5.4 to 8.1 kg or 12 to 17 pounds: 4 to 11 months: 80 mg

8.2 to 10.8 kg or 18 to 23 pounds: 1 to 2 years: 120 mg

10.9 to 16.3 kg or 24 to 35 pounds: 2 to 3 years: 160 mg

16.4 to 21.7 kg or 36 to 47 pounds: 4 to 5 years: 240 mg

21.8 to 27.2 kg or 48 to 59 pounds: 6 to 8 years: 320 mg

27.3 to 32.6 kg or 60 to 71 pounds: 9 to 10 years: 400 mg

32.7 to 43.2 kg or 72 to 95 pounds: 11 years: 480 mg

The manufacturer recommends the use of weight to select the dose as the preferred method. If weight is not available, then age may be used.

Rectal: 10 to 20 mg/kg/dose every 4 to 6 hours as needed (Although the perioperative use of high dose rectal Acetaminophen Injection (e.g., 25 to 45 mg/kg/dose) has been investigated in several studies, its routine use remains controversial; optimal doses and dosing frequency to ensure efficacy and safety have not yet been established; further studies are needed).

Children greater than or equal to 12 years:

IV: Less than 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours

Maximum single dose: 750 mg/dose

Maximum total daily dose: 75 mg/kg/day (less than or equal to 3750 mg/day)

IV: Greater than or equal to 50 kg: 650 mg every 4 hours or 1000 mg every 6 hours

Maximum single dose: 1000 mg/dose

Maximum total daily dose: 4000 mg/day

Oral or Rectal: 325 to 650 mg every 4 to 6 hours or 1,000 mg 3 to 4 times daily

Maximum daily dose: 4000 mg/day

Acetaminophen Injection interactions

What other drugs will affect Acetaminophen Injection?

Acetaminophen Injection is metabolized (eliminated by conversion to other chemicals) by the liver. Therefore drugs that increase the action of liver enzymes that metabolize Acetaminophen Injection [for example, carbamazepine (Tegretol), isoniazid (INH, Nydrazid, Laniazid), rifampin (Rifamate, Rifadin, Rimactane)] reduce the levels of Acetaminophen Injection and may decrease the action of Acetaminophen Injection. Doses of Acetaminophen Injection greater than the recommended doses are toxic to the liver and may result in severe liver damage. The potential for Acetaminophen Injection to harm the liver is increased when it is combined with alcohol or drugs that also harm the liver.

Cholestyramine (Questran) reduces the effect of Acetaminophen Injection by decreasing its absorption into the body from the intestine. Therefore, Acetaminophen Injection should be administered 3 to 4 hours after cholestyramine or one hour before cholestyramine.

Acetaminophen Injection doses greater than 2275 mg per day may increase the blood thinning effect of warfarin (Coumadin) by an unknown mechanism. Therefore, prolonged administration or large doses of Acetaminophen Injection should be avoided during warfarin therapy

Acetaminophen Injection side effects

• swelling, pain, or tenderness in the upper abdomen or stomach area

For Healthcare Professionals

Applies to Acetaminophen Injection: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository

General

In general, Acetaminophen Injection (the active ingredient contained in Acetaminophen Injection) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.

Nervous system

Common (1% to 10%): Headache, dizziness

Frequency not reported: Dystonia

Common (1% to 10%): Muscle spasms, trismus

Psychiatric

Common (1% to 10%): Insomnia, anxiety

Genitourinary

Common (1% to 10%): Oliguria

Local

Common (1% to 10%): Infusion site pain, injection site reactions

Ocular

Common (1% to 10%): Periorbital edema

Other

Common (1% to 10%): Pyrexia, fatigue

Rare (0.01% to 0.1%): Malaise

References1. “Multum Information Services, Inc. Expert Review Panel”

2. Zimmerman HJ, Maddrey WC “Acetaminophen Injection (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure.” Hepatology 22 (1995): 767-73

3. Vitols S “Paracetamol hepatotoxicity at therapeutic doses.” J Intern Med 253 (2003): 95-8

4. Gursoy M, Haznedaroglu IC, Celik I, Sayinalp N, Ozcebe OI, Dundar SV “Agranulocytosis, plasmacytosis, and thrombocytosis followed by a leukemoid reaction due to acute Acetaminophen Injection toxicity.” Ann Pharmacother 30 (1996): 762-5

5. Kurtovic J, Riordan SM “Paracetamol-induced hepatotoxicity at the recommended dosage.” J Intern Med 253 (2003): 240-3

6. McJunkin B, Barwick KW, Little WC, Winfield JB “Fatal massive hepatic necrosis following Acetaminophen Injection overdose.” JAMA 236 (1976): 1874-5

7. Minton NA, Henry JA, Frankel RJ “Fatal paracetamol poisoning in an epileptic.” Hum Toxicol 7 (1988): 33-4

8. Cheung L, Meyer KC “Acetaminophen Injection poisoning and liver function.” N Engl J Med 331 (1994): 1311-2

9. Rumore MM, Blaiklock RG “Influence of age-dependent pharmacokinetics and metabolism on Acetaminophen Injection hepatotoxicity.” J Pharm Sci 81 (1992): 203-7

10. Kumar S, Rex DK “Failure of physicians to recognize Acetaminophen Injection hepatotoxicity in chronic alcoholics.” Arch Intern Med 151 (1991): 1189-91

11. Block R, Jankowski JA, Lacoux P, Pennington CR “Does hypothermia protect against the development of hepatitis in paracetamol overdose?” Anaesthesia 47 (1992): 789-91

12. Hartleb M “Do thyroid hormones promote hepatotoxicity to Acetaminophen Injection?” Am J Gastroenterol 89 (1994): 1269-70

13. Lee WM “Acute liver failure.” Am J Med 96 (1994): 3-9

14. Whitcomb DC, Block GD “Association of acetaminopphen hepatotoxicity with fasting and ethanol use.” JAMA 272 (1994): 1845-50

15. Kaysen GA, Pond SM, Roper MH, Menke DJ, Marrama MA “Combined hepatic and renal injury in alcoholics during therapeutic use of Acetaminophen Injection.” Arch Intern Med 145 (1985): 2019-23

16. Mofenson HC, Caraccio TR, Nawaz H, Steckler G “Acetaminophen Injection induced pancreatitis.” Clin Toxicol 29 (1991): 223-30

17. Keays R, Harrison PM, Wendon JA, et al “Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial.” BMJ 303 (1991): 1026-9

18. Singer AJ, Carracio TR, Mofenson HC “The temporal profile of increased transaminase levels in patients with Acetaminophen Injection-induced liver dysfunction.” Ann Emerg Med 26 (1995): 49-53

19. Bonkovsky HL “Acetaminophen Injection hepatotoxicity, fasting, and ethanol.” JAMA 274 (1995): 301

20. Brotodihardjo AE, Batey RG, Farrell GC, Byth K “Hepatotoxicity from paracetamol self-poisoning in Western Sydney: a continuing challenge.” Med J Aust 157 (1992): 382-5

21. Lee WM “Medical progress: drug-induced hepatotoxicity.” N Engl J Med 333 (1995): 1118-27

22. Johnson GK, Tolman KG “Chronic liver disease and Acetaminophen Injection.” Ann Intern Med 87 (1977): 302-4

23. Keaton MR “Acute renal failure in an alcoholic during therapeutic Acetaminophen Injection ingestion.” South Med J 81 (1988): 1163-6

24. Smilkstein MJ, Douglas Dr, Daya MR “Acetaminophen Injection poisoning and liver function.” N Engl J Med 331 (1994): 1310-1

25. Shriner K, Goetz MB “Severe hepatotoxicity in a patient receiving both Acetaminophen Injection and zidovudine.” Am J Med 93 (1992): 94-6

26. Whitcomb DC “Acetaminophen Injection poisoning and liver function.” N Engl J Med 331 (1994): 1311

27. Bonkovsky HL, Kane RE, Jones DP, Galinsky RE, Banner B “Acute hepatic and renal toxicity from low doses of Acetaminophen Injection in the absence of alcohol abuse or malnutrition – evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency.” Hepatology 19 (1994): 1141-8

28. O’Dell JR, Zetterman RK, Burnett DA “Centrilobular hepatic fibrosis following Acetaminophen Injection-induced hepatic necrosis in an alcoholic.” JAMA 255 (1986): 2636-7

29. Block R “Liver failure induced by paracetamol.” BMJ 306 (1993): 457

30. Cheung L, Potts RG, Meyer KC “Acetaminophen Injection treatment nomogram.” N Engl J Med 330 (1994): 1907-8

31. Bray GP “Liver failure induced by paracetamol.” BMJ 306 (1993): 157-8

32. Seeff LB, Cuccherini BA, Zimmerman HJ, Adler E, Benjamin SB “Acetaminophen Injection hepatotoxicity in alcoholics.” Ann Intern Med 104 (1986): 399-404

33. Wong V, Daly M, Boon A, Heatley V “Paracetamol and acute biliary pain with cholestasis.” Lancet 342 (1993): 869

34. Nelson EB, Temple AR “Acetaminophen Injection hepatotoxicity, fasting, and ethanol.” JAMA 274 (1995): 301

35. Halevi A, BenAmitai D, Garty BZ “Toxic epidermal necrolysis associated with Acetaminophen Injection ingestion.” Ann Pharmacother 34 (2000): 32-4

36. Settipane RA, Stevenson DD “Cross sensitivity with Acetaminophen Injection in aspirin-sensitive subjects with asthma.” J Allergy Clin Immunol 84 (1989): 26-33

37. Kalyoncu AF “Acetaminophen Injection hypersensitivity and other analgesics.” Ann Allergy 72 (1994): 285

38. Doan T, Greenberger PA “Nearly fatal episodes of hypotension, flushing, and dyspnea in a 47- year-old woman.” Ann Allergy 70 (1993): 439-44

39. Leung R, Plomley R, Czarny D “Paracetamol anaphylaxis.” Clin Exp Allergy 22 (1992): 831-3

40. Kawada A, Hiruma M, Noguchi H, Ishibashi A “Fixed drug eruption induced by Acetaminophen Injection in a 12-year-old girl.” Int J Dermatol 35 (1996): 148-9

41. Doan T “Acetaminophen Injection hypersensitivity and other analgesics – response.” Ann Allergy 72 (1994): 285

42. Van Diem L, Grilliat JP “Anaphylactic shock induced by paracetamol.” Eur J Clin Pharmacol 38 (1990): 389-90

43. Bougie DW, Benito AI, Sanchez-Abarca LI, Torres R, Birenbaum J, Aster RH “Acute thrombocytopenia caused by sensitivity to the glucuronide conjugate of Acetaminophen Injection.” Blood 109 (2007): 3608-9

44. Shoenfeld Y, Shaklai M, Livni E, Pinkhas J “Thrombocytopenia from Acetaminophen Injection.” N Engl J Med 303 (1980): 47

45. Guccione JL, Zemtsov A, Cobos E, Neldner KH “Acquired purpura fulminans induced by alcohol and Acetaminophen Injection – successful treatment with heparin and vitamin-k.” Arch Dermatol 129 (1993): 1267-9

46. Thomas RH, Munro DD “Fixed drug eruption due to paracetamol.” Br J Dermatol 115 (1986): 357-9

47. Filipe PL, Freitas JP, Decastro JC, Silva R “Drug eruption induced by Acetaminophen Injection in infectious mononucleosis.” Int J Dermatol 34 (1995): 220-1

48. Kondo K, Inoue Y, Hamada H, Yokoyama A, Kohno N, Hiwada K “Acetaminophen Injection-induced eosinophilic pneumonia.” Chest 104 (1993): 291-2

49. Brown G “Acetaminophen Injection-induced hypotension.” Heart Lung 25 (1996): 137-40

50. Koulouris Z, Tierney MG, Jones G “Metabolic acidosis and coma following a severe Acetaminophen Injection overdose.” Ann Pharmacother 33 (1999): 1191-4

Some side effects of Acetaminophen Injection may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Acetaminophen Injection contraindications

What is the most important information I should know about Acetaminophen Injection?

There are many brands and forms of Acetaminophen Injection available and not all brands are listed on this leaflet.

Do not take more of this medication than is recommended. An overdose of Acetaminophen Injection can damage your liver or cause death.

Know the amount of Acetaminophen Injection in the specific product you are taking.

Do not take this medication without a doctor’s advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You may not be able to take Acetaminophen Injection.

Avoid drinking alcohol. It may increase your risk of liver damage while taking Acetaminophen Injection.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have liver disease or a history of alcoholism.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen Injection (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much Acetaminophen Injection which can lead to a fatal overdose. Check the label to see if a medicine contains Acetaminophen or APAP.

Active ingredient matches for Acetaminophen Injection:

More about Acetaminophen Injection