The effects of oxycodone don’t last longer than a few hours in most cases, but does that mean that the drug is out of your system that quickly?
Once oxycodone is in your bloodstream, your body starts to filter it out gradually over time. This means after the drug peaks, you’ll start to feel less pain relief, and the other effects (such as euphoria) may lessen, too.
A peak is when the amount of drug in your bloodstream reaches its highest. The peak usually happens around two hours after you take the drug if it’s a short-acting formula. If it’s a long-acting formula, then it may peak around six hours.
This can vary depending on other factors, such as the last time you ate or what other medications you’re taking.
By six hours after taking a 5mg oxycodone dose, pain relief and other effects have usually ended. This can take up to 12 hours for a long-acting 30mg oxycodone dose.
Even though the pain relief and “high” have ended, oxycodone is still in your system at this point. It may show up in your urine, blood, saliva, or hair on a drug test.
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